منابع مشابه
Reactivating Memories for Consolidation
The consolidation of memory is thought to occur via a hippocampal-neocortical dialog involving reactivation of memory patterns in the hippocampus during sharp-wave ripples. In this issue of Neuron, Nakashiba et al. demonstrate that CA3 output is required for consolidation of contextual fear memory. They also show that lack of CA3 output results in a decrease in ripple-related reactivation, prov...
متن کاملMemory retrieval: Reactivating sensory cortex
Associating information with vivid sensory cues aids recall of that information. New experiments help shed some light on the brain mechanisms of memory retrieval that make this mnemonic technique so effective.
متن کاملIdentification and expression of the genes encoding a reactivating factor for adenosylcobalamin-dependent glycerol dehydratase.
Adenosylcobalamin-dependent glycerol dehydratase undergoes inactivation by glycerol, the physiological substrate, during catalysis. In permeabilized cells of Klebsiella pneumoniae, the inactivated enzyme is reactivated in the presence of ATP, Mg2+, and adenosylcobalamin. We identified the two open reading frames as the genes for a reactivating factor for glycerol dehydratase and designated them...
متن کاملDNA demethylation is superior to histone acetylation for reactivating cancer-associated genes in ovarian cancer cells.
To investigate the contributions of histone H3 lysine 9 acetylation and DNA methylation to p16, hMLH1 and MGMT silencing in ovarian cancer cells, we treated three ovarian cancer cell lines with Trichostatin A (TSA) and 5-aza-2'-deoxycytidine and examined the status of mRNA expression, DNA methylation and histone H3 lysine 9 acetylation at the promoter of p16, hMLH1 and MGMT. The results showed ...
متن کاملStability monitoring of some acetylcholinesterase reactivating drugs
Background Widespread use of organophosphorous compounds (OPs) in agriculture and as nerve agents as well as a lack of clinically effective antidotes initiated the synthesis of new pyridinium bis-aldoximes (K-compounds) with high potency in reactivating acetylcholinesterase irreversibly inhibited by OPs [1,2]. We aimed to optimize an HPLC method sensitive enough to determine K-compounds from di...
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ژورنال
عنوان ژورنال: Genome Biology
سال: 2001
ISSN: 1465-6906
DOI: 10.1186/gb-spotlight-20010516-02